| ncRNA name | RHPN1-AS1 |
| ncRNA Category | lncRNA |
| ID | 100048912 |
| Ensembl | ENSG00000254389 |
| Synonyms | C8orf51, MGC3113 |
| Disease name | uveal melanoma (UM) |
| Species | Homo sapiens |
| Tissues/Cell_line | UM cell line OM431, OCM1; RPE cells |
| Methods | qRT-PCR, fluorescencein situ hybridization, cell migration assay, cell invasion assay, colony formation assay, xenograft, microarray |
| Expression pattern | up-regulated |
| Functional description | RHPN1-AS1 knockdown significantly inhibited UM cell proliferation and migration in vitro and in vivo. Our data suggest that RHPN1-AS1 could be an oncoRNA in UM, which may serve as a candidate prognostic biomarker and target for new therapies in malignant UM. |
| PubMed ID | 28124977 |
| Year | 2017 |
| Title | The Long Non-Coding RNA RHPN1-AS1 Promotes Uveal Melanoma Progression. |
| Drug-related ncRNA | NO |
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